It's not identified regardless of whether modafinil passes into breast milk or if it could hurt a nursing baby. Tell your health care provider If you're breast-feeding a infant.
Allergic reactions like rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome may well seldom be activated by an immunological response to modafinil or its metabolites.
Browse all individual info, medication guides, and instruction sheets furnished to you personally. Talk to your doctor or pharmacist When you have any queries.
Minimal (one)modafinil will enhance the stage or impact of rabeprazole by impacting hepatic enzyme CYP2C19 metabolism. Slight/Significance Unidentified. Web effect on pantoprazole actions unknown resulting from opposing results of CYP450 enzymes; keep an eye on
The usage of modafinil as a intended cognitive enhancer could possibly be considered as dishonest, unnatural, or dangerous.[236] The College of Sussex described that it is a prescription drug and the choice should be produced by the health practitioner on no matter if to prescribe modafinil to your student.[237] As a issue of bioethics, the US President's Council on Bioethics argued that excellence accomplished with the usage of drugs like modafinil is "inexpensive" mainly because it obviates the need for hard work and research, and isn't totally authentic because the excellence is partly attributable for the drug, not the person.
Orexin can be a neurotransmitter that is certainly considered to play a job in stimulating Over-all arousal and wakefulness. Determined by this, some researchers have speculated that modafinil’s effect on orexin may perhaps contribute to its Main stimulatory effects [35].
modafinil will enhance the stage or outcome of clobazam by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Dosage adjustment could possibly be required; CYP2C19 inhibitors may well bring about improved publicity to N-desmethylclobazam (Energetic metabolite).
Prescription drugs which have step therapy associated with Each individual prescription. This restriction normally requires that specific standards be satisfied previous to approval to the click here prescription.
Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig revurdere langtidsbruk for den enkelte pasient ettersom effekten av modafinil ved langtidsbruk ikke har blitt studert (>9 uker). Spesielle pasientgrupper Nedsatt leverfunksjon: Ved alvorlig nedsatt leverfunksjon bør dosen halveres.
fedratinib will increase the degree or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Regulate dose of medicine which might be CYP3A4 substrates as essential.
Should you be taking modafinil to deal with sleepiness due to obstructive slumber apnea, you may also be dealt with having a continuous positive airway stress (CPAP) machine.
In South Africa, modafinil is Program V material, which implies that it's authorized to utilize modafinil in South Africa, but only with a valid prescription from the licensed health care practitioner.[211]
Tilstand som skyldes inntak av giftige stoffer, slik som legemidler, rusmidler, kjemikalier eller stoffer som finnes naturlig i dyr og planter, i en slik mengde at det kan føre til alvorlig skade.
stiripentol will raise the level or influence of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Carefully. Contemplate lessening the dose of CYP2C19 substrates, if adverse reactions are seasoned when administered concomitantly with stiripentol.